>NC_002645_HCoV-229E_inf-1_nsp2_626..2983_2358bp_786aa
--NVTYTDQYLCGADGKPVMS--------------EDLWQFVDHFGENEE--IIINGHTY
VCAWLTKR---------KPLDYKR-QNNLAIEEIEYVHGDALHTLRNGSVLEMAKEVKTS
SKVV-LSDALDKLYKVFGSP--VMTNGSNILEAFTKPVFISALVQCTCGTKSWSVGDWTG
FKSSCCNVISNKLC-----VVPGNVKPGDAVITTQQAGAGIKY--FCGMTLKFVANIE--
----GVSVWRVIALQSVDCFVASSTFVEEEHVNRMDTFCFNVRNSVTDECRLAMLGAEMT
SNVRRQVASGVIDISTGWFDVYDDIFAESKPWFVRKAEDIFGPCWSALASALKQLKVTTG
ELVRFVKSICNSAVAVVGGTIQILASVPEKFLNAFDVFVTAIQTVFDCAVETCTIAGKAF
DKV---FDYVLLDNALVKLVTTKLKGVRERGLNKVKYATVVVGSTEEVKSS-RVERSTAV
LTIANNYSKLFDEGYTVVIGDVAYFVSDGYFRLMASPNSVLTTAVYKP------LFAFNV
NVMGTRPEKFPTTVTC---ENLESAVLFVNDKITEF---QLDYSIDVIDNEIIVKPNI-S
LCVPLYVRDYVDKWDDFCRQYSNESWFEDDYRAFISVLDITDAAV---KAAESKAFVDTI
VPPCPSILKVIDGGKIWNGVIKNVNSVRDWLKSL--KLNLTQQGLLGTCAKRFKRWLGIL
LE--------------AYNAFLDTVVSTVKIGGLTFKTYAF-DKPY--IVIRDIVCKVEN
KTEAEWIELFPHNDRIKSFSTFESAYMPIADPTHFDI----EEVEL-----LDAEFVEPG
-CGGILAVIDEHVFYKKDGV----YYPSNGTN-ILPVA---FTKAAG
>NC_005831_HCoV-NL63_AmsterdamI_nsp2_617..2980_2364bp_788aa
--SVVFVDKYMCGFDGKPVLP--------------KNMWEFRDYFNNNTD-SIVIGGVTY
QLAWDVIR---------KDLSYEQ-QNVLAIESIHYL-GTTGHTLKSGCKLTNAKPPKYS
SKVV-LSGEWNAVYRAFGSP--FITNGMSLLDIIVKPVFFNAFVKCNCGSESWSVGAWDG
YLSSCCGTPAKKLC-----VVPGNVVPGDVIITSTSAGCGVKY--YAGLVVKHITNIT--
----GVSLWRVTAVHSDGMFVASSSYDALLHRNSLDPFCFDVNTLLSNQLRLAFLGASVT
EDVKFAASTGVIDISAGMFGLYDDILTNNKPWFVRKASGLFDAIWDAFVAAIKLVPTTTG
VLVRFVKSIASTVLTVSNGVIIMCADVPDAFQSVYRTFTQAICAAFDFSLDVFKIGDVKF
KRL---GDYVLTENALVRLTTEVVRGVRDARIKKAMFTKVVVGPTTEVKFS-VIELATVN
LRLVDCAPVVCPKGKIVVIAGQAFFYSGGFYRFMVDPTTVLNDPVFTG------DLFYTI
KFSGFKLDGFNHQFVTA--SSATDAIIAVELLLLDFKTAVFVYTCVVDGCSVIVRRDA-T
FATHVCFKDCYNVWEQFCIDNCGEPWFLTDYNAILQSNNPQCAIV---QASESKVLLERF
LPKCPEILLSIDDGHLWNLFVEKFNFVTDWLKTL--KLTLTSNGLLGNCAKRFRRVLVKL
LD--------------VYNGFLETVCSVAYTAGVCIKYYAV-NVPY--VVISGFVSRVIR
RERCDMT--FPCVSCVTFFYEFLDTCFGVSKPNAIDV----EHLEL-----KETVFVEPK
-DGGQFFVSGDYLWYVVDDI----YYPASCNG-VLPVA---FTKLAG
>NC_002306_TGEV_PUR46-MAD_nsp2_639..2951_2313bp_771aa
-RGAIYVDQYMCGADGKPVIE-----------------GDFKDYFGDEDI--IEFEGEEY
HCAWTTVR---------DEKPLNQ-QTLFTIQEIQYN-LDIPHKLPNCATRHVAPPVKKN
SKIV-LSEDYKKLYDIFGSP--FMGNGDCLSKCFDTLHFIAATLRCPCGSESSGVGDWTG
FKTACCGLSGKVKG-----VTLGDIKPGDAVVTSMSAGKGVKF--FANCVLQYAGDVE--
----GVSIWKVIKTFTVDETVCTPGFEGELND----FIKPESKSLVACSVKRAFITGDID
DAVHDCIITGKLDLSTNLFGNVGLLF-KKTPWFVQKCGALFVDAWKVVEELCGSLTLTYK
QIYEVVASLCTSAFTIVNYKPTFVV-PDNRVKDLVDKCVKVLVKAFDVFTQIITIAGIEA
KCFVLGAKYLLFNNALVKLVSVKILGKKQKGLECAFFATSLVGATVNVTPK-RTETATIS
LNKVD-DVVAPGEGYIVIVGDMAFYKSGEYYFMMSSPNFVLTNNVFKAVKVPSYDIVYDV
DNDTKSKMIAKLGSSFEYDGDIDAAIVKVNELLIEFRQQSLCFRAFKDDKSIFVEAYFKK
YKMPACLAKHIGLW-NIIKKDSCKRGFLNLFNHLNELEDIKETNI---------QAIKNI
L--CPDPLLDLDYGAIWYNCMPGC---SD--PSVLGSVQLLIGNGVKVVCDGCKGFANQL
SK--------------GYNKLCNAARNDIEIGGIPFSTFKTPTNTF--IEMTDAIYSVIE
QGKAL---------------SFRDADVPVVDNGTISTADWSEPILL-----EPAEYVKPK
-NNGNVIVIAGYTFYKDEDEH---FYPY-GFGKIVQRM---YNKMGG
>NC_003436_PEDV_CV777_nsp2_627..2981_2355bp_785aa
--NIVPVDQYMCGADGKPVLQ--------------ESEWEYTDFFADSEDGQLNIAGITY
VKAWIVER---------SDVSYAS-QNLTSIKSITYC-STYEHTFLDGTAMKVARTPKIK
KNVV-LSEPLATIYREIGSP--FVDNGSDARSIIRRPVFLHAFVKCKCGSYHWTVGDWTS
YVSTCCGFKCKPVL-----VASCSAMPGSVVVTRAGAGTGVKY--YNNMFLRHVADID--
----GLAFWRILKVQSKDDLACSGKFLEHHEEGFTDPCYFLNDSSLATKLKFDILSGKFS
DEVKQAIIAGHVVVGSALVDIVDDAL--GQPWFIRKLGDLASAPWEQLKAVVRGLGLLSD
EVVLFGKRLSCATLSIVNGVFEFLADVPEKLAAAVTVFVNFLNEFFESACDCLKVGGKTF
NKV---GSYVLFDNALVKLVKAKARGPRQAGICEVRYTSLVVGSTTKVVSK-RVENANVN
LVVVDEDVTLNTTGRTVVVDGLAFFESDGFYRHLADADVVIEHPVYKS------ACELKP
VFECDPIPDFPLPVA----ASVAELCVQTDLLLKNYNTPYKTYSCVVRGDKCCITCTL-Q
FKAPSYVEDAVN-FVDLCTKNIGTAGFHEFYITAHEQQDLQGFLTTCCTMSGFECFM-PT
IPQCPAVLEEIDGGSIWRSFITGLNTMWDFCKRL--KVSFGLDGIVVTVARKFKRLGALL
AE--------------MYNTYLSTVVENLVLAGVSFKYYAT-SVPK--IVLGGCFHSVKS
VFASVFQ--IPVQAGIEKFKVFLNCVHPVV-PRVIET----SFVEL-----EETTF-KPP
ALNGGIAIVDGFAFYYDGTL----YYPTDGNS-VVPIC---FKKKGG
>DQ811787_PRCV_ISU-1_nsp2_628..2940_2313bp_771aa
-RGVIYVDQYMCGADGKPVIE-----------------GDFKDYFGDEDI--IEFEGEEY
HCAWTTVR---------DEKPLNQ-QTLFTIQEIQYN-LDIPHKLPNCATRHVAPPVKKN
SKIV-LSEDYKKLYDIFGSP--FMGNGDCLSKCFDTLHFIAATLRCPCGSESSGVGDWTG
FKTACCGLSGKVKG-----VTLGDIKPGDAVVTSMSAGKGVKF--FANCVLQYAGDVE--
----GVSIWKVIKTFTVDETVCTLGFEGELND----FIKPESKSLIACSVKRAFITGEID
DAVHDCIITGKLDLSTNLFGNVGLLF-KKPPWFVQKCGALFVDAWKVVEELCGSLTLTYK
QIYEVVASLCNSVFTIVNYKPTFVV-PDNRVKDLVDKCVKVLVKAFDVFTQNIIIAGIEA
KCFVLGAKYLLFNNALVKLVSVKILGKKQKGLECAFFATSLVGATANVTPT-RTETATIS
LNKVD-DVVAPGEGYIVIVGDMAFYKSGEYYFMMSSPNSVLTNNVFKAVKVPSYDIVYDV
DNDTKSKMIAKLGSSFEYDGDIDAAIVKVNELLIEFRQQSLCFRALKDDKTIFVEAYFKK
YKMPACLANHIGLW-NIIKKDSCKKGFLNLFNHLNELEDIKETNI---------QAIKNI
L--CPDPLLDLDYGAIWYNCMPSC---SD--SSVLGSVQLLIGNGVKVVCDGCKGFANQL
SK--------------GYNKLCNAARNDIEIGGIPFSTFKTPTNTF--IEMTDAIYSVVE
QGEAL---------------SFRDADVPVVDDGTIATVDWSEPILL-----EPAEYVKPK
-NNGNVIVIAGYTFYKDEDEH---FYPY-GFGKIVQRM---YNKMGG
>AY994055_FIPV_79-1146_nsp2_641..2947_2307bp_769aa
---AIYVDQYMCGADGKPVIE-----------------GEFKDYFGDEDV--IIYEGEEY
HCAWLTVR---------DEKPLWQ-QTLLTIREIQYN-LDIPHKLPNCAIREVAPPVKKN
SKVV-LSEEYRKLYDIFGSP--FMGNGDSLNTCFDSLHFIAATLKCPCGAESSGVGDWTG
FKTACCGLHGKVKG-----VTLGAVKPGDAIVTSMSAGKGVKF--FANSVLQYAGDVE--
----NVSVWKVIKTFTVNETVCTTDFEGELND----FIRPESTSPVSCSIKRAFITGEVD
DAVHDCIIAGKLDLSTNLFGSANLLF-KKMPWFVQKCGAIFADAWKVVEELLCSLKLTYK
QIYDVVASLCTSAFTIMDYKPVFVV-SSNSVKDLVDKCVKILVKAFDVFTQTITIAGVEA
KCFVLGSKYLLFNNALVKLVSVKILGKRQKGLDSAFFATNLIGATVNVTPQ-RTESAYIS
LNKVD-DVVTPGGGHIVIIGDMAFYKSEEYYFMMASPDSVLVNNVFKAARVPSYNIVYDV
NDDTKSKMVVKIGTSFDFDGDLDAAIAKVNDLLIEFRQEKLCFRALKDGENILVEAYLKK
YKMPVCLKNHVGLW-DIIRQDSGKKGFLDTFNHLNELEDVKDIKI---------QTIKNI
I--CPDLLLELDFGAIWYRCMPAC---SD--KSILGNVKIMLGNGVKVVCDGCHSFANRL
TI--------------NYNKLCDTARKDIEIGGIPFSTFKTPSSSF--IDMKDAIYSVVE
YGEAL---------------SFKTASVPVTNSGIITTDDWSDPILL-----EPADYVEPK
-DNGDVIVIAGYTFYKDEDDH---FYPY-GSGMVVQKM---YNKMGG
>NC_009657_BtCoV-G1_BtCoV/512/2005_nsp2_624..2984_2361bp_787aa
--TTIPVDQFMCGADGAPVIQ--------------EGDWTFMDYFQDSNQ--FTLNGITY
VKAWDVDR---------KPNDYAK-QNVTCIRRITYI-TDHRHVLADGTTMKTARHPKVN
KSVV-LDSPFDQIYKEVGSP--FMGNGSTFVEMLKDPAFFHALITCECGRSEWTVGDWKG
YNSLCCNIKCKPIT-----IVTPKAVPGAVVITKAGIGAGLKC--YNNVFLKHIIDLVVP
GTNLGWGVWRIAKVQSKDDVATSGNVLVDDPEDRLDPCYFGNDGPFATKFKFQLLANSFD
DEVKGAIVQGVVHVNTAICDVVKDIL--GLPWFVKKLGSLVTVMWDQFVAGVQSMKICTL
KVVQLAKALSCATMSVVKGVITLVAEVPEIFKRLFYTLTSALKSLCTSSCDALVVAGKSF
AKI---GDYVLLPSALVRLVSSKVKGKAQSGIKQLQFATVVLGDTHKVESD-RVEFSSVN
LKMVDEEFPLNPVGHTVAVGNQAFFCSDGLYRFMADRDLVITSPIFKP------ELELEP
IFECDAIPGFPKVAA----SNVAELCVKVDTLLFNYDKIYKKYSTIIKGDRCYIQCTH-T
FKAPSYYFDD-DEFVELCTKYYKLPDFDAFYNAVHAATDMDQF---CALCTSGFEVFIPR
VPDCPPILNDIDGGSIWTSFILSVRSATDFIKTL--KIDLGLNGVVVFVTKKFRKAGALL
QK--------------LYNAFLDTVTSFIKVAGVAFKYCAT-CVPK--IVINGCYHTVTR
LFAKDLQ--IPTEDGVADFNTFNHCVFPV-NPTRIET----DSLEL-----EEVDFVEPG
-VDGKLVILDDYSFYSDGTN----YYPSDGKG-VVASC---FKKKGG
>EF203064_Bat-CoV-HKU2_HKU2/GD/430/2006_nsp2_627..2984_2358bp_786aa
--DVVPVDNYMCGADGKPAVP--------------SEQWSFVEHFDDDTD-EITVNGVTF
RHAWNTVR---------ADDPYEK-QGLLSIKFIEYI-SNVPHKLPNGSVLGVAGTPKKR
KAVV-LDEKYSKLYDACGVP--FVTNGKSISEVVTKPLFLHALVECKCGNESWTVGDWTG
FKTTCCGVTGKVIT-----LAVGDVTPGDIVFTTPGAGKGTKF--FCGLVLTFVDTLE--
----GVSAWRVVKAYTVDKFVASSNFDEHNHVMSLDQCSFDNFSPISVALKFSLLRGNCC
DDVKVAVATGVIDIGLGVFDVNDTVF-ENVPWFVQKF-EFLKPAWDALKQAIINLGVTSK
AVLSFIKSLCSAAFSVVDGVPVIVCTVAERFSKAFTDFLSYTRECFTALCDDIVVFGVKC
KAV---GDYIIFNNSVVKTVKAKIKGVKEAGLKTMTYTQCLLGPTKPVKVK-RVERSVAQ
LKVVDTAVPLKQEGECLVVGGRAMFRSDGYYRFMADADVVLESPVFTA------GSQYNV
VFETDALFIAPEIGTVFEGDNIDTVVQTVANKVQAFNNRFVVYNAHVVDGAINVFCDY-K
FICPAFLDGF-PEWFSFCKNHFKDAGFVEFYDCII--NSDSTFQTTFQPYLDLKPSVDAY
L--GPEIVRAVDGGRLWRTVINGIGDAVNFCKNL--RLHFEFGELKGTVVKRFKGILGTL
LT--------------VYNEFIQTTVSVLTICGISAKYYAF-DKPM--LCMHGITERVTS
FDITSLG--KPILDGLSRCNVFARGSNAVVVDS-VDH----ELLDL-----EECDFVEPA
-SHGVLVVSDDYGFYSCETG----IYPYASDGKVLPLR---FRKKAG
>NC_005147_HCoV-OC43_OC43_nsp2_949..2763_1815bp_605aa
VKPLLYVDQYGCDYTGSLADGLEAY-----ADKTLQEMKALFPTWSQELL-------FDV
IVAWHVVR---------DPRYVMRLQSAATIRSVAYV-ANPTEDLCDGSV-----VIKEP
VHVYADDSIILRQYNLVDIMSHFYMEADTVVNA-----FYGVALK-DCGFVMQF-----G
YID-CEQDSCDFKG-----WIPGNMIDGFACTT-----CGHVY--EVGDLIAQSSGVL--
---------------PVNPVLHTKSAAG--------------YGGFGCKDSFTLYGQTVV
Y-FGGCVY---------WSPARN--------------------IWIPILKSS--------
-----VKSYDSLVYTGVLGCKAIVKETNLICKALYLDYVQHKCG----NLHQRELLGVSD
VW----HKQLLLNRGVYKPLLENIDYFNMRRAKFSLETFTVCADGFMPFLL---------
------DDLVPRAYYLAVSG--------QAFCDYADK------------------LCHAV
VSKSKELLDVSL-------DSLGAAIHYLNSKIVDL------AQHFSDFGTSFVSKIVHF
FKTFTTSTALAFAWVLFHVLHGAYIVVESDI-----------------------------
------------------YFVKNI---PRYASAVAQAFQSVAKVVLDSLRVTFIDGL---
-------------------SCFKIGRRRICLSGRKIYEVERGLLHS--SQLPLDVYDLTM
PSQVQKAKQKPI-------YLKGSGSDFSLADSVVEV----VTTSL-----TPCGYSEPP
KVADKICIVDNVYMAKAGDK----YYPVVVDD-HVGLLDQAWRVPCA
>NC_006577_CoV-HKU1A_N1_nsp2_872..2632_1761bp_587aa
IKPVLFVDQYGCDYSGKLADCLQAY-----GHYSLQDMRQKQSVWLANCD-------FDI
VVAWHVVR---------DSRFVMRLQTIATICGIKYV-AQPTEDVVDGDV-----VIREP
VHLLSADAIVLKLPSLMKVM--THMDDFSIKS------IYNVDL-CDCGFVMQY-----G
YVD-CFNDNCDFYG-----WVSGNMMDGFSCPL-----CCTVY--DSSEVKAQSSGVI--
---------------PENPVLFTNSTDTVNHD------------------SFNLYGYSVT
P-FGSCIY---------WSPRPG--------------------LWIPIIKSS--------
-----VKSYDDLVYSGVVGCKSIVKETALITHALYLDYVQCKCG----NLEQNHILGVNN
SW----CRQLLLNRGDYNMLLKNIDLFVKRRADFAC-KFAVCGDGFVPFLL---------
------DGLIPRSYYLIQSG--------IFFTSLMSQ------------------FSQEV
SDMCLKMCILFM-------DRVSVATFYIEHYVNRL------VTQFKLLGTTLVNKMVNW
FNTMLDASAPATGWLLYQLLNGLFVVSQANF-----------------------------
------------------NFVALI---PDYAKILVNKFYTFFKLLLECVTVDVLKDM---
-------------------PVLKTINGLVCIVGNKFYNVSTGLIPG--FVLPCNAQEQ--
----------------QIYFFEGVAESVIVEDDVIEN----VKSSL-----SSYEYCQPP
KSVEKICIIDNMYMGKCGDK----FFPIVMNDKNICLLDQAWRFPCA
>AY884001_CoV-HKU1B_N2_nsp2_866..2626_1761bp_587aa
IKPVLFVDQYGCDYSGKLADCLQAY-----GHYSLQDMRQKQSVWLANCD-------FDI
VVAWHVVR---------DSRFVMRLQTIATICGIKYV-AQPTEDVVDGAV-----VIREP
VHLLSADAIVLKLPSLMKVM--THMDDFSIKS------IYNVDL-CDCGFVMQY-----G
YVD-CFNDNCDFYG-----WVSGNMMDGFSCPL-----CCTVY--DSSEVKAQSSGVI--
---------------PENPVLFTNSTDTVNPD------------------SFNLYGYSVT
P-FGSCIY---------WSPRPG--------------------LWIPIIKSS--------
-----VKSYDDLVYSGVVGCKSIVKETALITHALYLDYVQCKCG----NLEQNHILGVNN
SW----CRQLLLNRGDYNMLLKNIDLFVKRRADFAC-KFAVCGDGFVPFLL---------
------DGLIPRSYYLIQSG--------IFFTSLMSQ------------------FSQEV
SDMCLKMCILFM-------DRVSVATFYIEHYVNRL------VTQFKLLGTTLVNKMVNW
FNTMLDASAPATGWLLYQLLNGLFVVSQANF-----------------------------
------------------NFVALI---PDYAKILVNKFYTFFKLLLECVTVDVLKDM---
-------------------PVLKTINGLVCIVGNKFYNVSTGLIPG--FVLPCNAQEQ--
----------------QIYFFEGVAESVIVEDDVIEN----VKSSL-----SSYEYCQPP
KSVEKICIIDNMYMGKCGDK----FFPIVMNDKNICLLDQAWRFPCA
>DQ339101_CoV-HKU1C_N5_nsp2_866..2626_1761bp_587aa
IKPVLFVDQYGCDYSGKLADCLQAY-----GHYSLQDMRQKQSVWLANCD-------FDI
VVAWHVVR---------DSRFVMRLQTIATICGIKYV-AQPTEDVVDGDV-----VIREP
VHLLSADAIVLKLPSLMKVM--THMDDFSIKS------IYNVDL-CDCGFVMQY-----G
YVD-CFNDNCDFYG-----WVSGNMMDGFSCPL-----CCTVY--DSSEVKAQSSGVI--
---------------PENPVLFTNSTDTVNPD------------------SFNLYGYSVT
P-FGSCIY---------WSPRPG--------------------LWIPIIKSS--------
-----VKSYDDLVYSGVVGCKSIVKETALITHALYLDYVQCKCG----NLEQNHILGVNN
SW----CRQLLLNRGDYNMLLKNIDLFVKRRADFAC-KFAVCGDGFVPFLL---------
------DGLIPRSYYLIQSG--------IFFTSLMSQ------------------FSQEV
SDMCLKMCILFM-------DRVSVATFYIEHYVNRL------VTQFKLLGTTLVNKMVNW
FNTMLDASAPATGWLLYQLLNGFFVVSQANL-----------------------------
------------------NFVALI---PDYAKILVNKFYTFFKLLLECVTVDVLKDM---
-------------------PVLKTINGLVCIVGNKFYNVSTGLIPG--FVLPCNAQEQ--
----------------QIYFFEGVAESVIVEDDVIEN----VKSSL-----SSYEYCQPP
KSVEKICIIDNMYMGKCGDK----FFPIVMNDKNICLLDHAWRFPCA
>NC_003045_BCoV_BCoV-ENT_nsp2_949..2763_1815bp_605aa
VKPLLYVDQYGCDYTGGLADGLEAY-----ADKTLQEMKALFPIWSQELP-------FDV
TVAWHVVR---------DPRYVMRLQSASTIRSVAYV-ANPTEDLCDGSV-----VIKEP
VHVYADDSIILRQHNLVDIMSCFYMEADAVVNA-----FYGVDLK-DCGFVMQF-----G
YID-CEQDLCDFKG-----WVPGNMIDGFACTT-----CGHVY--ETGDLLAQSSGVL--
---------------PVNPVLHTKSAAG--------------YGGFGCKDSFTLYGQTVV
Y-FGGCVY---------WSPARN--------------------IWIPILKSS--------
-----VKSYDGLVYTGVVGCKAIVKETNLICKALYLDYVQHKCG----NLHQRELLGVSD
VW----HKQLLLNRGVYKPLLENIDYFNMRRAKFSLETFTVCADGFMPFLL---------
------DDLVPRAYYLAVSG--------QAFCDYADK------------------ICHAV
VSKSKELLDVSL-------DSLSAAIHYLNSKIVDL------AQHFSDFGTSFVSKIVHF
FKTFTTSTALAFAWVLFHVLHGAYIVVESDI-----------------------------
------------------YFVKNI---PRYASAVAQAFRSVAKVVLDSLRVTFIDGL---
-------------------SCFKIGRRRICLSGSKIYEVERGLLHS--SQLPLDVYDLTM
PSQVQKAKQKPI-------YLKGSGSDFSLADSVVEV----VTTSL-----TPCGYSEPP
KVADKICIVDNVYMAKAGDK----YYPVVVDG-HVGLLDQAWRVPCA
>NC_001846_MHV_MHV-A59_nsp2_951..2705_1755bp_585aa
VKPILFVDQYGCDYTGCLAKGLEDY-----GDLTLSEMKELFPVWRDSLD-------SEV
LVAWHVDR---------DPRAAMRLQTLATVRCIDYV-GQPTEDVVDGDV-----VVREP
AHLLAANAIVKRLPRLVETM--LYTDSSVTE-------FCYKTKLCECGFITQF-----G
YVD-CCGDTCDFRG-----WVAGNMMDGFPCPG-----CTKNY--MPWELEAQSSGVI--
---------------PEGGVLFTQSTDTVNRE------------------SFKLYGHAVV
P-FGSAVY---------WSPCPG--------------------MWLPVIWSS--------
-----VKSYSGLTYTGVVGCKAIVQETDAICRSLYMDYVQHKCG----NLEQRAILGLDD
VY----HRQLLVNRGDYSLLLENVDLFVKRRAEFAC-KFATCGDGLVPLLL---------
------DGLVPRSYYLIKSG--------QAFTSMMVN------------------FSHEV
TDMCMDMALLFM-------HDVKVATKYVKKVTGKL------AVRFKALGVAVVRKITEW
FDLAVDIAASAAGWLCYQLVNGLFAVANGVI-----------------------------
------------------TFVQEV---PELVKNFVDKFKAFFKVLIDSMSVSILSGL---
-------------------TVVKTASNRVCLAGSKVYEVVQKSLSA--YVMPVGCSEATC
--------------------LVGEIEPAVFEDDVVDV----VKAPL-----TYQGCCKPP
TSFEKICIVDKLYMAKCGDQ----FYPVVVDNDTVGVLDQCWRFPCA
>NC_007732_PHEV_VW572_nsp2_949..2763_1815bp_605aa
VKPLLYVDQYGCDYTGGLADGLEAY-----ADKTLQEMKALFPIWSQELP-------FDV
TVAWHVVR---------DPRYVMRLQSASTIRSVAYV-ANPTEDLCDGSV-----VIKEP
VHVYADDSIILRQHNLVDIMSCFYMEADAVVNA-----FYGVDLK-DCGFVMQF-----G
YID-CEQDLCDFKG-----WVPGNMIDGFACTT-----CGHVY--ETGDLLAQSSGVL--
---------------PVNPVLHTKSAAG--------------YGGFGCKDSFTLYGQTVV
Y-FGGCVY---------WSPARN--------------------IWIPILKSS--------
-----VKSYDSLVYTGVVGCKAIVKETNLICKALYLDYVEHKCG----NLHQRELLGVSD
VW----HKQLLLNRGVYKPLLENIDYFNMRRAKFSLETFTVCADGFMPFLL---------
------DDLVPRAYYLAVSG--------HAFCDYADK------------------LCHAV
VSKSKDLLDVSL-------DSLGAAIHYLNFKIVDL------AQHFSDFGASFVSTIVRY
FKTFTTSTALAFAWVLFHVLHGAYIVVESDI-----------------------------
------------------YFVKNI---PRYASAVAQAFRSVAKVVLDSLRVTFIDGL---
-------------------SCFKIGRRRICLSGRKIYEVERGLLHS--SQLPLDVYDLTM
PSQVQKAKQKPI-------YLKGSGSDFSLADSVVEV----VTTSL-----TPCGYSEPP
KFADKICIVDNVYMAKAGDK----YYPVVVDD-HVGLLDQAWRVPCA
>EF424621_AntelopeCoV_US/OH1/2003WD1418_nsp2_934..2748_1815bp_605aa
VKPLLYVDQYGCDYTGGLADGLEAY-----ADKTLQEMKALFPIWSQELP-------FDV
TVAWHVVR---------DPRYVMRLQSASTIRSVAYV-ANPTEDLCDGSV-----VIKEP
VHVYADDSIILRQHNLVDIMSCFYMEADAVVNA-----FYGVDLK-DCGFVMQF-----G
YID-CEQDLCDFKG-----WVPGNMIDGFACTT-----CGHVY--ETGDLLAQSSGVL--
---------------PVNPVLHTKSAAG--------------YGGFGCKDSFTLYGQTVV
Y-FGGCVY---------WSPARN--------------------IWIPILKSS--------
-----VKSYDGLVYTGVVGCKAIVKETNLICKALYLDYVQHKCG----NLHQRELLGVSD
VW----HKQLLLNRGVYKPLLENIDYFNMRRAKFSLETFTVCADGFMPFLL---------
------DDLVPRAYYLAVSG--------QAFCDYADK------------------ICHAV
VSKSKELLDVSL-------DSLSAAIYYLNSKIVDL------AQHFSDFGTSFVSKIVHF
FKTFTTSTALAFAWVLFHVLHGAYIVVESDI-----------------------------
------------------YFVKNI---PRYASAVAQAFRSVAKVVLDSLRVTFIDGL---
-------------------SCFKIGRRRICLSGSKIYEVERGLLHS--SQLPLDVYDLTM
PSQVQKAKQKPI-------YLKGSGTDFSLADSVVEV----VTTSL-----TPCGYSEPP
KVADKICIVDNVYMAKAGDK----YYPVVVDG-HVGLLDQAWRVPCA
>EF424622_GiCoV_US/OH3-TC/2006_nsp2_933..2747_1815bp_605aa
VKPLLYVDQYGCDYTGGLADGLEAY-----ADKTLQEMKALFPIWSQELP-------FDV
TVAWHVVR---------DPRYVMRLQSASTIRSVAYV-ANPTEDLCDGSV-----VIKEP
VHVYADDSIILRQHNLVDIMSCFYMEADAVVNA-----FYGVDLK-DCGFVMQF-----G
YID-CEQDLCDFKG-----WVPGNMIDGFACTT-----CGHVY--ETGDLLAQSSGVL--
---------------PVNPVLHTKSAAG--------------YGGFGCKDSFTLYGQTVV
Y-FGGCVY---------WSPARN--------------------IWIPILKSS--------
-----VKSYDGLVYTGVVGCKAIVKETNLICKALYLDYVQHKCG----NLHQRELLGVSD
VW----HKQLLLNRGVYKPLLENIDYFNMRRAKFSLETFTVCADGFMPFLL---------
------DDLVPRAYYLAVSG--------QAFCDYADK------------------ICHAV
VSKSKELLDVSL-------DSLSAAIYYLNSKIVDL------AQHFSDFGTSFVSKIVHF
FKTFTTSTALAFAWVLFHVLHGAYIVVESDI-----------------------------
------------------YFVKNI---PRYASAVAQAFRSVAKVVLDSLRVTFIDGL---
-------------------SCFKIGRRRICLSGSKIYEVERGLLHS--SQLPLDVYDLTM
PSQVQKAKQKPI-------YLKGSGTDFSLADSVVEV----VTTSL-----TPCGYSEPP
KVADKICIVDNVYMAKAGDK----YYPVVVDG-HVGLLDQAWRVPCA
>NC_004718_SARS-human_Tor2_nsp2_805..2718_1914bp_638aa
AVTRYVDNNF-CGPDGYPLDCIKDFLA--RAGKSMCTLSEQLDYIESKRG-VYCCRDHEH
EIAWFTER---------SDKSYEH-QTPFEIKSAKKF-DTFKGECPKFVF-----PLNSK
VKVI-QPRVEKK--KTEGFM--GRIRS-----------VYPVASPQECNNMHLS-----T
LMK-C--NHCDEVS-----WQTCDFLK-ATCEH-----CGTENLVIEG---PTTCGYL--
---------------PTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRC
--FGGCVFA--------YVGCYNKRA-----------------YWVPRASAD--------
---------IGSGHTGITG---------DNVETLNEDLLEILSR---ERVNINIVGDFHL
N-----EEVAIILASFSASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGK--PVKGAWN
IGQQR-SVLTPLCGFPSQAA--------GVIRSIFARTL---------------DAANHS
IPDLQRAAVTIL-------DGISEQSLRLVDAMV--------YTSDLLTNSVIIMAYV--
---TGGLVQQTSQWLSNLLGTTVEK-------------------------------LRPI
FEWIEAKL------SAGVEFLKDA---WEILKFLITGVFDIVKGQIQVASDNIKDCVKCF
ID--------------VVNKALEMCIDQVTIAGAKLRSLNLGEVF---IAQSKGLYRQCI
RGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVL----KNGELEALE-TPVDSFTNG
AIVGTPVCVNGLMLLEIKDKE---QYCALSPG--LLATNNVFRLKGG
>AY304488_SARS-civet_SZ16_nsp2_790..2703_1914bp_638aa
AVTRYVDNNF-CGPDGYPLDCIKDFLA--RAGKSMCTLSEQLDYIESKRG-VYCCRDHEH
EIAWFTER---------SDKSYEH-QTPFEIKSAKKF-DTFKGECPKFVF-----PLNSK
VKVI-QPRVEKK--KTEGFM--GRIRS-----------VYPVASPQECNNMHLS-----T
LMK-C--NHCDEVS-----WQTCDFLK-ATCEH-----CGTENLVIEG---PTTCGYL--
---------------PTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRC
--FGGCVFA--------YVGCYNKRA-----------------YWVPRASAD--------
---------IGSGHTGITG---------DNVETLNEDLLEILSR---ERVNINIVGDFHL
N-----EEVAIILASFSASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGK--PVKGAWN
IGQQR-SVLTPLCGFPSQAA--------GVIRSIFSRTL---------------DAANHS
IPDLQRAAVTIL-------DGISEQSLRLVDAMV--------YTSDLLTNSVIIMAYV--
---TGGLVQQTSQWLSNLLGTTVEK-------------------------------LRPI
FEWIEAKL------SAGVEFLKDA---WEILKFLITGVFDIVKGQIQVASDNIKDCVKCF
ID--------------VVNKALEMCIDQVTIAGAKLRSLNLGEVF---IAQSKGLYRQCI
RGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVL----KNGELEALE-TPVDSFTNG
AIVGTPVCVNGLMLLEIKDKE---QYCALSPG--LLATNNVFRLKGG
>NC_009694_SARS-bat_HKU3-1_nsp2_802..2715_1914bp_638aa
VVTRYVDNNF-CGPDGYPLECIKDFLA--RAGKSMCTLSEQLDYIESKRG-VYCCREHEH
EIVWFTER---------SEKSYEH-QTPFEIKSAKKF-DTFKGECPKFVF-----PLNSK
VKVI-QPRVEKK--KTEGFM--GRIRS-----------VYPVATPQECNDMHLS-----T
LMK-C--NHCDEVS-----WQTCDFLK-ATCEQ-----CGTENLVCEG---PTTCGYL--
---------------PTNAVVKMPCPACQDPEVGPEHSVADYHNHSNIETRLRKGGRTKC
--FGGCVFS--------YVGCYNKRA-----------------YWVPRASAN--------
---------IGANHTGITG---------ENVETLNEDLLEILNR---ERVNINIVGDFRF
N-----EEVAIILASFSASPSAFIETVKGLDYKSFKVIVESCGNYKVTNGK--PVTGAWN
IGQQR-SILTPLCGFPSQAA--------GVIRSIFSRTL---------------DAANHS
ILDLQRAAVTTL-------DGISEQSLRLVDAMV--------YTSDLLTNSVVVMAYV--
---TGGLVQQTMQWLSNMLGTAVDK-------------------------------LKPV
FTWVEAKL------SAGVEFLRDA---WEILKFLITGVFDVIKGQIQVATDNIKECVKIF
LG--------------VVNKALEMCLDQVTIAGTKLRALNLGEVF---IAQSRGLYRQCI
RGKEQLQLLMPLKAPKEVTFLEGDAHDTVLTSEEVVL----KSGELEALE-TPIDSFTSG
AVVGTPVCINGLMLLELENKE---QYCALSPG--LLATNNVFRLKGG
>AY545919_SARS-badger_CFB/SZ/94/03_nsp2_784..2697_1914bp_638aa
AVTRYVDNNF-CGPDGYPLDCIKDFLA--RAGKSMCTLSEQLDYIESKRG-VYCCRDHEH
EIAWFTER---------SDKSYEH-QTPFEIKSAKKF-DTFKGECPKFVF-----PLNSK
VKVI-QPRVEKK--KTEGFM--GRIRS-----------VYPVASPQECNNMHLS-----T
LMK-C--NHCDEVS-----WQTCDFLK-ATCEH-----CGTENLVIEG---PTTCGYL--
---------------PTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRC
--FGGCVFA--------YVGCYNKRA-----------------YWVPRASAD--------
---------IGSGHTGITG---------DNVETLNEDLLEILSR---ERVNINIVGDFHL
N-----EEVAIILASFSASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGK--PVKGAWN
IGQQR-SVLTPLCGFPSQAA--------GVIRSIFARTL---------------DAANHS
IPDLQRAAVTIL-------DGISEQSLRLVDAMV--------YTSDLLTNSVIIMAYV--
---TGGLVQQTSQWLSNLLGTTVEK-------------------------------LRPI
FEWIEAKL------SAGVEFLKDA---WEILKFLITGVFDIVKGQIQVASDNIKDCVKCF
ID--------------VVNKALEMCIDQVTIAGAKLRSLNLGEVF---IAQSKGLYRQCI
RGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVL----KNGELEALE-TPVDSFTNG
AIVGIPVCVNGLMLLEIKDKE---QYCALSPG--LLATNNVFRLKGG
>NC_009019_Bat-CoV-HKU4_B04f HKU41_nsp2_852..2807_1956bp_652aa
--DCIPIDQYMCGKNGKPIADYAKIVAK-EGLTTLADIEVDVKSRMDSDR-FIVLNKKLY
RVVWNVTR---------RNVPYPK-QTAFTIVSVVQC--DDKDSVPEHTF-----TIGSQ
ILMV-SPLKATN-NKNFNLK--QRLLYT----------FYGKDAVQQPGYIYHS-----A
YVD-C--NACGRGT-----WCTGNAIQGFACD------CGANY--SANDVDLQSSGLV--
---------------PRNALFLANCPCANNGACS--HSAAQVYNILDGKACVEVGGKSFT
LTFGGVVYA--------YMGCCDGTM-----------------YFVPRAKSC--------
-----VSRIGDAIFTGCTGTWDKVVETANLFLEKAQRSLNF-------------------
------CQQFALTEVVLAILSGTTSTFEELR--------DLCHNASYEKVR---------
------DHLVNH-GFVVTIG--------DYIRDA---------------------INIGA
NGVCNATINAPFIAF----TGLGESFKKVSAIPWKICSNLKSALDYYSSNIMF---RVFP
YDIPCDVSNFVELLLDCGKLTVATSYFVLRY------LDEKFDTVLGTVSSACQTALSSF
LNACVAAS------RATAGFINDM---FKLFKVLMHKLYVYTSCGYVAVAEHSSKIVQQV
LD--------------IMSKAMKLLHTNVSWAGTKLSAIIYEGREA--LLFNSGTYFCLS
TKAKTLQGQMNLVLPGDYNKKTLGILDPVPNADTIDVNANSTVVDVVHGQLEPTNEHGPS
MIVGNYVLVSDKLFVRTEDEE---FYPLCTNGKVVSTL---FRLKGG
>NC_009020_Bat-CoV-HKU5_LMH3f HKU51_nsp2_846..2813_1968bp_656aa
--DFTPIDQYMCGKNGKPIAEFAALMAS-EGITKLADVEAEVKSRTDSDR-YIVFKNKLY
RIVWNVQR---------KDVAYSK-QSAFTMNSIVQL--DTMEDVPRHSF-----TIGSE
IQVI-APSTAVQANGHLNLK--QRLLYA----------FYGKQAVSEPNYIYHS-----A
YVD-C--TSCGKGS-----WLTGNAVQGFACD------CGAHY--CANDVDLQSSGLV--
---------------RKNAVLLTTCPCNKDGECK--HTLPQLVSMMTDKCDVEVVGKTFI
LTYGGVIYA--------YMGCSGGTM-----------------HFIPRAKSC--------
-----VSKIGDAIFTGCTGTWSKVCETANLFLERAQHAINF-------------------
------VNEFVLTETVVALLSGTTSSIEELR--------DLCRNATFEKVR---------
------DYLTPR-GWIVTMG--------SYIEGV---------------------INVGA
AGVCNAALNAPFIVL----SGLGESFKKVAATPWKLCSSLRETLDHYADSITY---RVFP
YDIPCDVTDYTALLLDCAVLTGASAYFVARY------VDEKVEQLTNLVFSSCQSAVAAF
VQACMSTY------KATAKFISDM---FTLIKVVSERLYVYTSVGFVVVGDYSSQLLKQF
MH--------------ILSKAMQLLHTTVSWAGSKLPSVVYNGRDS--LVFPSGTYYCVS
TQGRSLQDQFDLVIPGDLSKKQIGILEPTPNSTTVDKKINTNVVEVVVGQLEPTKEHSPE
LVVGDYVIISNKIFVRSVEDSETVFYPLCTDGKIVPTL---FRLKGG
>NC_009021_Bat-CoV-HKU9_BF_005I HKU91_nsp2_754..2544_1791bp_597aa
--DVYLSDQYGFDNNGILVEPVMKLLGVIKSDFTLEQLLAALGKYRTEDG--YDLPDGYV
KVAIKVGR---------KAVPVLK-QSIFTVVGVT------EQLVPGYYY-----PFSTS
SVVE-HTKPTR-----GGPV--GKTVEA---------VMLSLYGTNNYNPATPV-----A
RLK-C--SYCDYYG-----WTPLKDIGTVNCL------CGAEFQLTSSCVDAESAGVI--
---------------KPGCVMLLDKSPG---------------------MRLIPGNRTYV
S-FGGAIWS--------PIGKVNGVT-----------------VWVPRAYSI--------
---------VAGEHSGAVGSGDTVAINKELVEYLIEGI----------RVDADTLDNPTC
A-----TFIANLDCDTKAPVVHTVESLQGL-----------CLANKIMLGD---------
------KPLPTDEFHPFIVG-----------------------------------LAYHV
QRACWYGALASRTF-----EAFRDFVRTEEERFAQF----FGKVCAPINGCVY-------
---LAYTTGRVTLFSAYQVLNTAIAKSKDAF---------------GGVAAIVVDMLKPI
LEWVLKKMSIAKG--AWLPYAEGL-------LALFKAQFTVVKGKFQFLRASLNSKCHSL
CD--------------LLTTIMSKLLTSVKWAGCKVDALYTGTYYY--FSRKGVLTEVQL
CAKRLGLLLTPKQQKMEVEVLDGDFDAPVTLTD-LELEECTGVLE------EVFGASDVK
LVKGTLVSLASKLFVRTEDGF---LYRYVKSGGVLGKA---FRLRGG
>NC_001451_IBV_Beaudette_nsp2_529..2547_2019bp_673aa
--MASSLKQGVSPKPRDVILV---------SKDIPEQLCDALFFYTSHNP-------KDY
ADAFAVRQKFDRSLQTGKQFKFETVCGLFLLKGVDKI------------------TPGVP
AKVLKATSKLADLEDIFGVS--PLARK------------YRELLKTACQWSLTV-----E
ALDVRAQTLDEIFDPTEILWLQVAAKIHVSS-------MAMRR--LVGEVTAKVMDAL--
--------------------------------------------GSNLSALFQIVKQQIA
RIFQKALA---------IFENVNELP------------QRIAALKMAFAKCARSITVVVV
ERTLVVKEFAGTCLASINGA------VAKFFEELPNGFMGSKIF----------------
------TTLAFFKEAAVRVVENIPNAPRGTK------GFEVVGNAKGTQVVVRGMRNDLT
LLDQKADIPVEPEGWSAILD--------GHLCYVFRSGDRFYAAPLSG------NFALSD
VHCCERVVCLSDGVTPEINDGLILAAIYSSFSVSELVTALKKGEPFKFLGHKFVYAKD--
-AAVSFTLAKAATIADVLRLFQSARVIAEDVWSSFTEKSFEFWKLAYGKVRNLEEFVKTY
V--CKAQMSIV---ILAAVLGEDI---WHLVSQVIYKLGVLFTKVVDFCDKHWKGFCVQL
KRAKLIVTETFCVLKGVAQHCFQLLLDAIHSLYKSFKKCALGRIHGDLLFWKGGVHKIVQ
DGDEIWFDAIDSVDVED---------LGVVQEKSIDF----EVCDD-----VTLPENQPG
HMVQIEDDGKNYMFFRFKKDENIYYTPMSQLGAINVVC------KAG
>AY646283_IBV-partridge_Partridge/GD/S14/2003_nsp2_331..2352_2022bp_674aa
--MASSLKQGVSSQNQRSVVLV--------AKDIPDQLRDALFFYTSHNP-------KDY
ADAFAFKRKFDRNLGAGKQFKFETVCGPFFLKGVDKV------------------TPGVP
AKVLKATSKLADLEDIFGVS--PFARK------------YRELLKTACQWSLTV-----D
ALNARAQTLEEIFGPTEVLWLQVASKLQVSA-------MAMRR--LVGEVTAKVMDAL--
--------------------------------------------GSKLSSLFQIVKQQIA
RIFQKALA---------IFEDVKDLP------------QRIAALQMAFAKCAKTITVVVV
EKAIVVREFSGTCLASINGA------IAKFFAELPNGFMGSKVF----------------
------STLAFFKEAAVKIVENVPGAPQGTK------GFEVVGNAKGTQVVIRGMRNDLT
LLDQKAEIPVEPEGWSAIMD--------GHLCYVFKSGDRFYAAPLSG------NFALHD
VHCCERVVCLVDGVTPEINDGLILAAIYSSFSVSELVAALKKGEPFKFLGHKFVYAKE--
-AAVSFTLAKAATISDVLKLFQSARVETEDVWSALTEKSFEFWKLAYGKVRNLEEFVKTH
F--CKAQMSIV---VLAVVLGEGI---WHLVSQVIYRLGCSFSKVIDFCAKYWKGFCGQL
KKAKLLVTEHLCVLKGVAQHCFQLLLDAIHSMYKSFQKCALGRIHGDLLFWKGGVHKVVQ
EGDEIWFDAIDSIDVEE---------LGVIQEKPVDF----EVCDG-----IILPENQPG
HMVQFEDDGKNYMFFRFKREDNVYYTPMSQLGAINVVC------KAG
>AY641576_IBV-peafowl_Peafowl/GD/KQ6/2003_nsp2_529..2547_2019bp_673aa
--MASSLKQGVSPKLRDVILV---------SKDIPEQLCDALFFYTSHNP-------KDY
ADAFAVRQKFDRNLQTGKQFKFETVCGLFLLKGVDKI------------------TPGVP
AKVLKATSKLADLEDIFGVS--PFARK------------YRELLKTACQWSLTV-----E
TLDARAQTLDEIFDSTEILWLQVAAKIQVSA-------MAMRR--LVGEVTAKVMEAL--
--------------------------------------------GSNLSVLFQIVKQQIA
RIFQKALA---------IFENVSELP------------QRIAALKMAFAKCAKSITVVVV
ERTLVVREFAGTCLASINGA------VAKFFEELPNGFMGSKIF----------------
------TTLAFFKEAAVKIVENIPNAPRGTR------GFEVVGNAKGTQVVVRGMRNDLT
LLDQKAEIPVESEGWSAILG--------GHLCYVFKSGDRFYAAPLSG------NFALHD
VHCCERVVCLSDGVTPEINDGLILAAIYSSFSVAELVAAIKRGEPFKFLGHKFVYAKD--
-AAVSFTLAKAATIADVLKLFQSARVKVEDVWSSLTEKSFEFWRLAYGKVRNLEEFVKTY
F--CKAQMAIV---ILATVLGEGI---WHLVSQVIYKVGGLFTKVVDFCEKYWKGFCAQL
KRAKLIVTETLCVLKGVAQHCFQLLLDAIQFMYESFKKCALGRIHGDLLFWKGGVHKIIQ
EGDEIWFDAIDSIDVED---------LGVVQEKLIDF----DVCDN-----VTLPENQPG
HMVQIEDDGKNYMFFRFKKDENIYYTPMSQLGAINVVC------KAG